A correlational study of Weifuchun and its clinical effect on intestinal...
AbstractBackgroundWeifuchun (WFC), a Chinese herbal prescription consisting of Red Ginseng, Isodon amethystoides and Fructus Aurantii, is commonly used in China to treat a variety of chronic stomach...
View ArticleNovel Variants of the SMARCA4 Gene Associated with Autistic Features Rather...
AbstractAutism spectrum disorders (ASDs) are a group of neurodevelopmental-related disorders with a high genetic risk. Recently, chromatin remodeling factors have been found to be related to ASDs....
View ArticleTrajectories of energy intake distribution and subsequent risk of...
AbstractAimsFew studies have examined the secular trend of the energy intake distribution, and its effect on future risk of hyperglycemia. This study aims to describe trajectories of energy intake...
View ArticleConcordance analysis of diatom types and patterns in lung tissue and drowning...
AbstractDiatom test has been widely used in the diagnosis of drowning and inferring the drowning site. One of the issues is whether the concordance of the diatom types and patterns between the drowning...
View ArticleClinical severity prediction in children with osteogenesis imperfecta caused...
AbstractSummaryOsteogenesis imperfecta (OI) is a genetic disease with an estimated prevalence of 1 in 13,500 and 1 in 9700. The classification into subtypes of OI is important for prognosis and...
View ArticleDeciphering the variations and mechanisms of the westerly jets across the...
AbstractUnderstanding the variations of the westerly jets (WJs) during the Last Interglacial (~ 127 ka; LIG) aids in deciphering the reconstructed hydrological conditions and dust activities at that...
View ArticleSodium content of restaurant dishes in China: a cross-sectional survey
AbstractBackgroundSodium intake in China is extremely high and eating in restaurants is increasingly popular. Little research has explored the sodium level of restaurant dishes. The present study aims...
View ArticleIdentification of Pathogenic Variants in RPGRIP1L with Meckel Syndrome and...
Abstract Meckel syndrome (MKS, OMIM:249000) is a severe multiorgan dysplastic lethal ciliopathy with extreme genetic heterogeneity. Defects in RPGRIP1L are the cause of MKS type 5 (MKS5, OMIM:611561)....
View ArticleA preliminary attempt on decadal prediction of the East Asian summer monsoon
AbstractThe East Asian summer monsoon (EASM) is one of the major synoptic systems that affect the summer climate in China. Decadal prediction of the EASM is of great significance, yet few attempts have...
View ArticleSystematic estimation of cystic fibrosis prevalence in Chinese and genetic...
AbstractBackgroundCystic fibrosis (CF) is a common, life-threatening genetic disease in Caucasians but rarely reported in Chinese population. The prevalence and population-specific genetic spectrum of...
View ArticleA novel and efficient CD22 CAR-T therapy induced a robust antitumor effect in...
AbstractBackgroundCD19 chimeric antigen receptor (CAR) therapy has achieved impressive success in relapsed or refractory (R/R) B-cell malignancies, but relapse due to antigen escape is increasingly...
View ArticleAssociation of gut microbiota with glycaemic traits and incident type 2...
AbstractAims/hypothesisThe gut microbiome is mainly shaped by diet, and varies across geographical regions. Little is known about the longitudinal association of gut microbiota with glycaemic control....
View ArticlePurine nucleoside analogs plus rituximab are an effective treatment choice...
Abstract Both characteristics and optimal treatment strategy for hairy cell leukemia-variant (HCL-v) remain elusive due to its rarity. We retrospectively analyzed the clinical features of HCL-v and the...
View ArticleFatigue Crack Growth Behavior of Eutectoid Steel Rail
AbstractThe fatigue crack behavior of U75V rail under different quenching rates was studied using SEM and CLSM. The results show that the pearlite interlayer spacing and fatigue crack growth rate...
View ArticleGut microbiota signatures of long-term and short-term plant-based dietary...
AbstractBackgroundThe interplay among the plant-based dietary pattern, gut microbiota, and cardiometabolic health is still unclear, and evidence from large prospective cohorts is rare. We aimed to...
View ArticleInfluence of postural changes on nasal resistance in patients with...
AbstractObjectiveIncreased nasal resistance (NR) can augment upper airway collapse in patients with obstructive sleep apnea (OSA). Posture change can lead to altered nasal resistance. Our study aimed...
View ArticleEstimation of hereditary fructose intolerance prevalence in the Chinese...
AbstractBackgroundHereditary fructose intolerance (HFI) caused by aldolase B reduction or deficiency that results in fructose metabolism disorder. The disease prevalence in the Chinese population is...
View ArticleCharacterizing the urban diet: development of an urbanized diet index
AbstractBackgroundIn recent decades China has experienced rapid urbanization leading to a major nutrition transition, with increased refined carbohydrates, added sweeteners, edible oils, and...
View ArticleDiagnostic challenge in mixed phenotype acute leukemia with T/megakaryocyte...
AbstractBackgroundThe diagnosis of mixed phenotype acute leukemia (MPAL) with T/megakaryocyte or T/myeloid lineages accompanied by t(3;3) is always a challenge. Therefore, multiple experimental methods...
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